View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Use of herbal products and potential interactions in patients with cardiovascular diseases. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). Unable to load your collection due to an error, Unable to load your delegates due to an error. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. The .gov means its official. This branded product is no longer on the market. If this worries you, talk to your doctor or pharmacist about other options. It is not intended as medical advice for individual conditions or treatment. This site complies with the HONcode standard for trustworthy health information: verify here. Which drugs or supplements interact with isosorbide mononitrate? Some conditions may become worse when the drug is suddenly stopped. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Accessed Sept. 7, 2022. Each day, take the first dose when you wake up, then take the second dose 7 hours later. Isosorbide tablets are also used with other medications to treat heart failure. isosorbide mononitrate, along with Store at room temperature away from light and moisture. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results.
Isosorbide mononitrate - UpToDate (2) One in 3 patients never experienced headache from the given dosages. Mayo Clinic. Things to remember when you fill your prescription. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). I strongly feel that there is coronary ischemia. [2] It is taken by mouth. https://naturalmedicines.therapeuticresearch.com. Isosorbide mononitrate (Monoket) can cause your blood pressure to drop somewhat. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. This list covers only some interactions. If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Saper RB. information is beneficial, we may combine your email and website usage information with It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Try to keep your regular appointments with your doctor. Bauer B (expert opinion). Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. All rights reserved. A randomized, double-blind, cross-over study. Drug interactions may change how your medications work or increase your risk for serious side effects. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. Patient is a UK registered trade mark. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . Glyceryl trinitrate (GTN) is commonly prescribed for this. It has a very short duration of action and may not be suitable for some people. But only about 25% of people who take herbal supplements tell their health care providers. Natural Medicines. If you miss a dose, take it as soon as you remember. Properly discard this product when it is expired or no longer needed. Longer-acting tablets and capsules are taken once daily in the morning. Some don't work well with prescription medicines. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. Hawthorn. Eur Heart J. There are 195 drugs known to interact with Isosorbide mononitrate helps to prevent angina chest pain from developing.
Isosorbide mononitrate | Drugs | BNF | NICE 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . To provide you with the most relevant and helpful information, and understand which Overview of herbal medicines and dietary supplements. Real test is coronary angiography. Garlic. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. Do not change the dosing times unless directed by your doctor. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). Does isosorbide mononitrate (Monoket) lower blood pressure? Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Journal of the American College of Cardiology. Contraindications: Isosorbide mononitrate should not be used in cases of acute myocardial infarction with low filling pressure, acute circulatory failure (shock, vascular collapse), or hypertrophic obstructive cardiomyopathy (HOCM), constrictive pericarditis, low cardiac filling pressures, aortic/mitral valve stenosis and diseases associated with a raised intra-cranial pressure e.g following a head trauma and including cerebral haemorrhage. Natural Medicines. Generic alternatives may be available. Then, there was a two-week placebo washout, after which the alternative treatment was given. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. include protected health information. Do not double the dose to catch up. You can take your doses either before or after meals. May also be prescribed off label for Esophageal Spasm. This is called a medicine interaction. It might help to keep the room cool and use a fan. Who should not take Isosorbide Mononitrate? Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. 8.0 out of 10 from a total of Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)?
Many herbal supplements can interact with prescription drugs. Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. Unless there is a specific reason you need the brand, the generic medication will be a better value. It will not treat an angina attack that has already begun. Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. https://naturalmedicines.therapeuticresearch.com. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Consult your doctor before breast-feeding. 67% of reviewers reported a positive effect, while 13% reported a negative effect.
Cardizem Alternatives Compared - Drugs.com Moderately clinically significant. Your dose may need to be gradually decreased. You can consult me online for homeopathic treatment. Coenzyme Q-10 Natural Medicines. Many people using this medication do not have serious side effects. Store in a cool, dry place, away from direct heat and light. Epub 2006 Mar 22. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. This content does not have an English version.
List of Antianginal agents (antianginal drugs) - Drugs.com If you notice any other effects, check with your healthcare professional. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Available for Android and iOS devices. Some of these medicine interactions can be risky. It is also important information to carry with you in case of emergencies. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Accessibility In Canada - Call your doctor for medical advice about side effects. Browse Drugs and Medicines. and transmitted securely. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Registered in England and Wales. An official website of the United States government. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. It can cause your blood pressure to become dangerously low. It is important that you follow the instructions your doctor gives to you about when to take your doses. What are the interactions of Isosorbide Mononitrate ? This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. Does Alcohol Raise Your Blood Pressure? Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. This content does not have an Arabic version. It is important to take the drug at the same times each day. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. It works to relax your blood vessels. Keep all medicines out of the reach and sight of children. https://naturalmedicines.therapeuticresearch.com. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. Keep all medications away from children and pets. Take the container with you, even if it is empty. Limited data from animal studies indicate no adverse effects on the pregnancy or the unborn child. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Do not let anyone else take your medication. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. Natural Medicines. The dose is according to the body weight and severity of the condition. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Isosorbide dinitrate dose 30-120 mg daily in divided doses. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals.
Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Avoid combinations; the risk of the interaction outweighs the benefit. Some don't work well with prescription medicines. Isosorbide controls chest pain but does not cure coronary artery disease. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. Side effects : headache, mild dizziness Heres what you need to know about alcohol and blood pressure including how alcohol can interact with your blood pressure medications. Background: Tachjian A, et al. We comply with the HONcode standard for trustworthy health information. information and will only use or disclose that information as set forth in our notice of Patient does not provide medical advice, diagnosis or treatment. Careers. Available for Android and iOS devices. The herb licorice may lower warfarin levels and can add to digoxin's effects. Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. Seek alternatives to the CYP3A4 substrate when possible. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). Compare a few possible alternatives below. FOIA Mayo Clinic; 2021. tell your doctor and pharmacist if you are allergic to isosorbide; nitroglycerin tablets, patches, or ointment; any other medications, or any of the ingredients in isosorbide tablets, extended-release tablets, or extended-release capsules. Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage. These headaches may be a sign that the medication is working as it should. What side effects can this medication cause? Alternative drugs to the conditions Isosorbide mononitrate treats: Angina High blood pressure Stable angina Chest pain Heart disease Heart attack Angina unstable Heart disease congenital Coronary heart disease Heart failure Pulse Heart rate irregular Coronary artery spasm Angioplasty My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms.
Consult your doctor for more details. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. Generic alternatives may be available. This document does not contain all possible drug interactions. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. The most common side-effect is headache. Consult your pharmacist or local waste disposal company. Do infrared saunas have any health benefits? Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. Accessed Sept. 7, 2022. This does not necessarily mean no interactions exist. All Rights Reserved.
Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use this medication regularly to get the most benefit from it. All rights reserved. Isosorbide mononitrate helps to prevent angina chest pain from developing.
Isosorbide mononitrate (Monoket): Basics, Side Effects & Reviews - GoodRx Isosorbide mononitrate belongs to the group of medicines called nitrates. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. For details see our conditions. Change positions slowly until your body is used to the medication. In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Isosorbide mononitrate helps to prevent angina chest pain from developing. Please upgrade your browser or download modern browsers from here! amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. Never take extra doses or stop taking it suddenly unless your provider tells you to do so. Nitrates in the management of acute coronary syndrome. Do not store in the bathroom. We study millions of patients and 5,000 more each day.
Isosorbide mononitrate Alternatives Compared - Drugs.com Alcohol can make the side effects from isosorbide worse. You need to take it every day in order for it to work.
Isosorbide Mononitrate - Uses, Side Effects, Substitutes, Composition Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature.
Isosorbide mononitrate - Wikipedia Portions of this document last updated: Feb. 01, 2023. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. On the other hand, the ER version can only help prevent angina. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. Danshen. If you have recently had a head injury or a heart attack. Selected from data included with permission and copyrighted by First Databank, Inc. Would you like email updates of new search results? There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. 1998 Oct;61(10):577-83. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Learn to reduce stress through mindful living. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. The most common side-effect is headache. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. If you have ever had an allergic reaction to a medicine. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. Diabetes treatment: Can cinnamon lower blood sugar? AHFS Patient Medication Information. Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Ask your doctor before using aspirin together with alcohol. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication.
Isosorbide mononitrate: effectiveness, side effects, alternatives What happens if I stop taking isosorbide mononitrate (Monoket)? Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect.
Imdur, Monoket (isosorbide mononitrate) dosing, indications - Medscape Aspirin has an average rating of Natural Medicines. What special precautions should I follow? Advertising revenue supports our not-for-profit mission. I took this for 4 days, and my headaches were unbearable. Bookshelf Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It is unknown if this medication passes into breast milk. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. . This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. Isosorbide mononitrate belongs to the group of medicines called nitrates. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Data were assessed for carryover and time effects. Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. Take extra precautions to avoid falling during your treatment with isosorbide.